Searchable abstracts of presentations at key conferences in endocrinology

ea0032p607 | Female reproduction | ECE2013

Main determinants of serum uric acid concentrations in polycystic ovary syndrome patients

Leustean Letitia , Preda Cristina , Ungureanu Maria Christina , Cristea Cristina , Mogos Voichita , Ungureanu Didona , Vulpoi Carmen

Introduction: Uric acid may increase cardiovascular risk, exerting proinflammatory, pro-oxidant and proliferative actions at the endothelial cell level. Classic and non-classic cardiovascular risk markers cluster in women with polycystic ovary syndrome (PCOS), uric acid being proposed as one of them. The studies available at present regarding serum uric acid levels in PCOS patients are scarce and controversial. The aim of the study was to examine the relationship between uric ...

ea0032p903 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Efficacy of hGH treatment in pituitary dwarfism- age does matter

Idriceanu Jeanina , Vasiliu Ioana , Popovici Ramona , Bodescu Ioana , Rusu Cristina , Mogos Voichita , Vulpoi Carmen

Introduction: The spectrum of GH deficiency (GHD) in children ranges from complete deficiency, with severe growth retardation, to partial deficiency, with slightly short stature. The administration of GH to children with GHD improves linear growth, mainly during the first 2 years of treatment.Patients and methods: The study analyzes pattern of growth in 35 children (24 boys, 11 girls) with GHD, in the first year of treatment with hGH. There were three gr...

ea0026p11 | Adrenal cortex | ECE2011

Arthritis after removal of adrenal adenoma in Cushing’s syndrome

Ungureanu Maria-Christina , Cernohuz Adriana , Gorduza Carmen , Scripcariu Viorel , Vulpoi Carmen , Preda Cristina

Endogenous hypercortisolism is a well-known immunosuppressive condition. Such endogenous cortisol secretion could suppress the clinical presentation of an ongoing autoimmune process.A 49-year-old woman was admitted in our service in august 2010 for Cushing clinical signs, arterial hypertension and hypokalemia. She had high plasma cortisol not suppressed by 1 and 8 mg dexamethasone overnight, low ACTH. Abdominal computed tomography demonstrated a tumor (3...

ea0026p430 | Thyroid (non cancer) | ECE2011

Improved prognosis in myxedema coma: happy ending of an old story: case report

Vasiliu Ioana , Preda Cristina , Grigoras Ioana , Florescu Alexandru , Balcan Roxana , Idriceanu Jeanina , Mogos Voichita , Vulpoi Carmen

Introduction: Myxedema coma (MC) is a rare life-threatening form of hypothyroidism most often seen in patients with incompletely treated or unknown hypothyroidism exposed to stressful conditions (surgery, infections, hypothermia, trauma).Case report: We report the case of a 58-years-old woman hospitalized for coma in a peripheral hospital after a severe respiratory infection. Two days after, patient’s condition was worsening and she was transferred ...

ea0026p521 | Bone/calcium/Vitamin D | ECE2011

Antagonism between body weight and adipocytokines on bone mass acquisition in pre- and postmenopausal women

Corina Buta , Dumitru Branisteanu , Cristina Preda , Didona Ungureanu , Ioana Gaspar , Roxana Novac , Voichita Mogos , Carmen Vulpoi

Introduction: Body weight is positively correlated to bone mineral density. The exact mechanism is unclear but gravity may be one of the involved factors. Adipocytokines (leptin and adiponectin), secreted by the adipose tissue, are involved in bone turnover. We investigated the influence of body weight, body composition, and adipocytokines upon bone mass in pre and postmenopausal women.Design: Cross-sectional study including six groups of 8 to 16 healthy...

ea0022p107 | Bone/Calcium | ECE2010

Parathyroid FNA with PTH determination as a tool in primary hyperparathyroidism diagnosis – case report

Idriceanu Jeanina , Ionescu Lidia , Miron Claudia , Balcan Roxana , ElMekkaoui Safae , Vasiliu Ioana , Mogos Voichita , Vulpoi Carmen

I fine-needle aspiration (FNA) is the gold standard in thyroid nodules management, but it is less common in the evaluation of parathyroid nodules. When imagery fails to localize a parathyroid adenoma, morphological and functional investigations, like FNA of the suspected area and scintigraphy may be useful. We present the case of a 58 years-old woman, menopaused at 47 years, who consulted for lombalgia. Vertebral DXA confirmed osteoporosis (Tscore −3.8). She was not trea...

ea0022p118 | Bone/Calcium | ECE2010

Primary hyperparathyroidism diagnosis – new insights of an old dilemma

Vulpoi Carmen , Stefanescu Cipriana , Ionescu Lidia , Crumpei Felicia , Vasiliu Ioana , Balcan Roxana , Idriceanu Jeanina , Mogos Voichita

Primary hyperparathyroidism (PHPT) is a relatively frequent problem in clinical endocrine practice. Minimally invasive parathyroid surgery is the treatment of choice but requires precise preoperatory localization. The most commonly investigation methods are ultrasonography and scintigraphy, but they are not always diagnostic. PTH assay of the aspirate from an ultrasound-guided fine-needle aspiration (USFNA) may confirm the location of pathological parathyroid tissue. The aim o...

ea0022p428 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Malignant paraganglioma – the story of a long time survival

Balcan Roxana , Iliescu Dan , Stefanescu Cipriana , Popa Radu , Vasiliu Ioana , Idriceanu Jeanina , Zbranca Eusebie , Vulpoi Carmen

Introduction: Pheochromocytoma and paraganglioma are catecholamine secreting tumours. Malignancy is uncommon (approximately 10% for pheochromocytoma and 20% for paraganglioma) and surgery, when possible, is the first line treatment. However, the prognosis is poor because of frequent local recurrence and/or metastases and the lack of specific chemotherapeutic agents. CASE-REPORT: We present the case of a 60 years-old man who, at the age of 48, was diagnosed with paraganglioma. ...

ea0022p803 | Thyroid | ECE2010

Thyroid lymphoma: a rare pathology: study on 9 cases

Mogos Voichita , Vulpoi Carmen , Burlacu Cristina , Cotea Elena , Niculescu Dan , Florea Niculina , Ciobanu Delia , Ferariu Dan

Thyroid lymphoma accounts for less than 5% of thyroid malignancies. The aim of this study was to analyze the particularities of 9 patients (7 females and 2 males, aged 42 to 76 years) diagnosed with thyroid lymphoma, representing 2.45% of 340 cases of thyroid malignancies. Patients were assessed by ultrasound examination (7 cases), fine needle biopsy (FNB) (8 cases), lymph node biopsy (2 cases), and histological examination after surgery (7 cases). Clinically, 6 cases presente...

ea0022p809 | Thyroid | ECE2010

Pitfalls in calcitonin measurement: case report

Vasiliu Ioana , Ciobanu Delia , Ungureanu Didona , Balcan Roxana , ElMekkaoui Safae , Idriceanu Jeanina , Mogos Voichita , Vulpoi Carmen

Calcitonin (CT) is a sensitive marker for medullary thyroid carcinoma, but its routine measurement in patients with thyroid nodules is a controversial issue. Generally, an elevated serum calcitonin strongly suggests the presence of medullary thyroid carcinoma (MTC); however high CT levels may be found in other thyroid or non-thyroidal conditions. We report the case of a 49-year-old woman who consulted at the ambulatory of endocrinology for recent thyroid soreness. Biological f...